Lysosomal Exocytosis Impacts Dectin-1 Endocytosis After β -Glucan Stimulation
نویسندگان
چکیده
منابع مشابه
Arabinoxylan activates Dectin-1 and modulates particulate β-glucan-induced Dectin-1 activation.
SCOPE Arabinoxylan is one of the most commonly consumed dietary fiber. Immunomodulation by arabinoxylan is documented but the mechanisms by which these immune-effects are accomplished are unknown. METHODS AND RESULTS By applying reporter cell lines for Toll-like receptors (TLRs) and Dectin-1, we demonstrated that arabinoxylan interacts with Dectin-1 receptors and not with TLRs. Arabinoxylan a...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2019
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2018.11.340